Tetracyclines

NaBrian J. Werth, PharmD, University of Washington School of Pharmacy
Imepitiwa/Imerekebishwa May 2024

Tetracyclines are a group of antibiotics used to treat many different bacterial infections.

Tetracyclines include the following:

  • Doxycycline

  • Eravacycline

  • Minocycline

  • Omadacycline

  • Tetracycline

Tetracyclines are usually taken by mouth and work by preventing bacteria from producing proteins they need to grow and multiply.

Tetracyclines should not be taken with products that contain aluminum, calcium, magnesium, or iron. Such products include some antacids and many vitamin and mineral supplements.

Tetracycline and omadacycline should be taken with plenty of water when the stomach is empty because food, especially dairy products such as milk, yogurt, cheese, and ice cream, reduces its absorption (the movement of a medication into the bloodstream after it is given by mouth).

Minocycline and doxycycline can be taken with or without food because food does not reduce their absorption.

Doxycycline, minocycline, and tetracycline can be given by injection as well as by mouth. Eravacycline can be given only by injection in a vein.

Jedwali

(See also Overview of Antibiotics.)

Matumizi ya Tetracyclines Wakati wa Ujauzito na Kunyonyesha

Pregnant women should avoid tetracyclines if possible. These antibiotics can affect tooth and bone development in the fetus and, if taken late in pregnancy, can cause permanent staining of the fetus's teeth. If a tetracycline must be used during pregnancy, doxycycline may be safer than others. (See also Safety of Medications During Pregnancy.)

Use of tetracyclines during breastfeeding is usually discouraged. (See also Medication and Substance Use During Breastfeeding.)