- Muhtasari wa Mfumo wa Neva za Pembeni
- Muhtasari wa Matatizo ya Magonjwa ya Mwungano wa Neva na Msuli
- Amyotrophic Lateral Sclerosis (ALS) na Magonjwa Mengine ya Mishipa ya Moyo (MNDs)
- Ugonjwa wa Charcot-Marie-Jino
- Upasuaji sugu wa Kuondoa Miyelinati ya Ugonjwa wa Uvimbe wa Mara kwa Mara (CIDP)
- Ugonjwa wa Eaton-Lambert
- Ugonjwa wa Guillain-Barré (GBS)
- Ugonjwa wa neva wa urithi wa macho
- Ugonjwa wa Neuropathy wa Kurithi na Dhima ya Kupooza kwa Shinikizo (HNPP)
- Ugonjwa wa Isaacs
- Uharibifu wa neva
- Mononeuropathy nyingi
- Myasthenia Gravisi
- Matatizo ya neva
- Matatizo ya Plexus
- Polineuropati
- Atrophies ya Misuli ya Uti wa mgongo (SMAs)
- Ugonjwa wa Mtu Mgumu
- Magonjwa ya Mifuko ya Kifua (TOS)
Hereditary neuropathies affect the peripheral nerves, causing subtle symptoms that worsen gradually.
(See also Overview of the Peripheral Nervous System.)
Hereditary neuropathies may affect only
Motor nerves (motor neuropathies)
Sensory and autonomic nerves (sensory neuropathies)
Sensory and motor nerves (sensory and motor neuropathies)
Motor nerves control muscle movement, and sensory nerves carry sensory information—about such things as pain, temperature, and vibration—to the brain. Autonomic nerves regulate involuntary body process.
Some hereditary neuropathies are relatively common but often are not recognized.
The genes responsible for many hereditary neuropathies and other hereditary disorders that cause neuropathies have been identified. The following are examples:
Some forms of Charcot-Marie-Tooth disease
When the sensory nerves are affected, the ability to feel pain and changes in temperature may be impaired more than the ability to sense vibration and position (knowing where the arms and legs are). The hands and feet are affected most. Because people cannot feel pain, they may injure their feet and not know it. Such injuries increase the risk of infections, including bone infections, and risk of joint damage (called neurogenic arthropathy, or Charcot joints). If the ability to sense vibration and position is affected, people have problems with balance and walking.
When motor nerves are affected, muscles weaken, waste away (atrophy), and can become completely paralyzed.
When autonomic nerves are affected, body processes do not function normally. For example, blood pressure may decrease when a person stands (called orthostatic hypotension), making the person feel dizzy or light-headed. Men may have difficulty initiating and maintaining an erection (erectile dysfunction). People may involuntarily pass urine (urinary incontinence) or have difficulty emptying the bladder (urine retention). Some people are severely constipated.
