Wingi wa nywele

(Hiriztizimu; Hypertrichosisi)

NaWendy S. Levinbook, MD, Hartford Dermatology Associates
Imepitiwa/Imerekebishwa Apr 2024

In men, the amount of body hair varies greatly (see also Overview of Hair Growth), but very few men are concerned enough about excess hair to see a doctor. In women, the amount of hair that is considered excessive varies depending on ethnic background and culture. Usually, excess body hair is only a cosmetic and psychological concern. However, the cause sometimes is a serious hormonal disorder, particularly in women who develop masculine characteristics (virilization).

Hairiness can be categorized as

  • Hirsutism

  • Hypertrichosis

Hirsutism is excessive growth of thick or dark body hair in women in locations that are more typical of male hair growth. Such locations include the face (on the upper lip, chin, or sideburn area), torso (around the nipples or on the chest, lower abdomen, or back), and limbs (on the shoulders or inner thighs).

Hypertrichosis is an increase in the amount of hair anywhere on the body in either sex. The excess hair may grow all over the body or only in specific locations. The hair may be fine, light-colored, and downlike or thick, dark, and long. This disorder may be present at birth or develop later.

Visababishaji vya Nywele zaidi

Hair growth depends on the balance between male and female hormones. Male hormones stimulate the growth of thick, dark hair. Women normally produce small amounts of male hormones, and men produce small amounts of female hormones.

Hiriztizimu

Hirsutism usually results from high levels of male hormones (androgens, such as testosterone) or from increased sensitivity to normal levels of male hormones in the body. Testosterone stimulates hair growth in the pubic area and underarms. Dihydrotestosterone stimulates hair growth in the beard area and hair loss on the scalp.

Conditions that tip the hormonal balance in favor of male hormones can cause hirsutism. The balance may be tipped by excess production of male hormones. However, in hirsutism that runs in families (familial hirsutism), women's hair follicles simply appear to be more sensitive to normal levels of male hormones.

The most common cause of hirsutism is

There are many less common causes of hirsutism (see table Some Causes and Features of Hirsutism):

  • Pituitary, ovarian, or adrenal gland disorders that result in overproduction of male hormones

  • Tumors that produce male hormones (including certain tumors of the ovaries, adrenal glands, lungs, or digestive tract)

  • Use of certain medications such as testosterone, danazol, or birth control pills (oral contraceptives) that have a high dose of progesterone or surreptitious use of anabolic steroids

  • A familial trait, most often occurring in people of Mediterranean, Middle Eastern, or South Asian descent

  • Sometimes after menopause or during pregnancy when hormone balance changes

When hirsutism is caused by increased levels of androgens, women often have virilization. Virilization is the development of masculine or other characteristics in addition to excess face and body hair. For example

  • The voice deepens.

  • Muscle size increases.

  • Hair is lost from the head.

  • The clitoris (the smaller female organ that corresponds to the penis) becomes larger.

  • Menstruation becomes irregular or stops completely.

  • Acne may also develop.

Hypertrichosis

Hypertrichosis is caused by disorders that do not affect the levels of male hormones.

The most common causes of hypertrichosis are

  • Certain complications of cancer (paraneoplastic syndromes)

  • Use of certain medications, most commonly minoxidil, phenytoin, cyclosporine, or the prostaglandin eye drops bimatoprost or latanoprost

  • A serious systemic disorder, such as HIV/AIDS, brain disorders or injuries, undernutrition (including eating disorders such as anorexia nervosa and bulimia), dermatomyositis, and porphyria

  • Repeated injury to and/or friction or inflammation of areas of skin (for example, an increase in hair growth that is noticed after a cast has been removed from a previously broken arm or leg)

Rarely, hypertrichosis is caused by a gene mutation. In such cases, it is usually present at birth.

Tathimini ya Nywele zaidi

Doctors must determine whether the excess hair results from a disorder or is simply a cosmetic concern.

Ishara za onyo

In women with excess body hair, certain symptoms are cause for concern:

  • Development of a deepened voice, increased muscle size, baldness, irregular or absent menstrual periods, and acne, which are signs of virilization

  • Sudden appearance and rapid growth of excess hair (over weeks to months)

  • A growth in the abdomen or pelvis

The sudden appearance of excess hair may suggest cancer.

Wakati wa kuona daktari

If warning signs are present, people should see a doctor promptly. If excess hair appears gradually without warning signs, people should see a doctor, but the visit does not need to be scheduled as quickly.

In general, women without warning signs do not need to see a doctor if they have always had excess hair, otherwise feel well, have regular menstrual periods, have no other signs of virilization, and have family members who also have excess hair. Such women have excess body hair because it runs in their family.

Anachofanya daktari

Doctors first ask questions about the person's symptoms and medical history. Doctors then do a physical examination. What they find during the history and physical examination often suggests a cause and the tests that may need to be done (see table Some Causes and Features of Hirsutism).

Women are asked when hair began to grow excessively and where it is located, whether they have menstrual periods, and, if so, whether periods are regular. Doctors also ask whether women have had problems conceiving a child and whether any family members also have excess hair.

Doctors ask people about all the medications and illicit drugs they are taking, particularly anabolic steroids and other drugs known to cause hair growth.

During the physical examination, doctors note the pattern of hair growth and look for other signs of virilization and for other features that suggest a cause. For example, a lump felt during the pelvic examination may suggest a tumor in an ovary.

Jedwali
Jedwali

Kupima

Men who have no other signs of illness do not undergo further testing.

Women have blood tests to measure levels of various hormones and thus help identify the cause:

  • Testosterone

  • Dehydroepiandrosterone sulfate (DHEAS)

  • Follicle-stimulating hormone (FSH) and luteinizing hormone (LH)

  • Sometimes prolactin

Kipimo cha Maabara
Kipimo cha Maabara

Ultrasonography and/or computed tomography (CT) or magnetic resonance imaging (MRI) of the pelvis may be done to rule out pelvic or adrenal cancer, particularly if a lump is found in the pelvis or if testosterone or DHEAS levels are high. If a pituitary disorder is suspected, MRI of the head is done.

If Cushing syndrome is suspected or an adrenal tumor is detected with imaging studies, urine tests are also done.

Matibabu ya Nywele zaidi

  • Treatment of the underlying condition, including stopping medications or illicit drugs that cause hairiness

  • Bleaching or hair removal for cosmetic enhancement

  • Hormone therapy

The underlying condition is treated or corrected. For example, medications and illicit drugs that may cause hirsutism are stopped or changed.

Treatment for the excess hair is unnecessary unless women wish to minimize or remove it for cosmetic reasons. If excess hair growth is not related to increased levels of male hormones, physical methods are used to remove the hair. If increased levels of male hormones are the cause, hormone therapy is needed in addition to physical methods.

Mbinu za kimwili

Several methods are available.

Depilation removes the part of the hair above the surface of the skin. Methods include shaving and over-the-counter creams, which may contain barium sulfate and/or calcium thioglycolate.

Epilation involves removing intact hairs with their roots. Methods to temporarily remove hairs include tweezing, plucking, waxing, and epilating devices used at home. Some methods have longer-lasting, sometimes permanent effects, but the treatments often must be repeated. These methods include electrolysis, thermolysis, and laser treatments.

Tiba ya homoni

Usually, hormones used to treat hirsutism must be taken for a long time because most of the disorders that cause high male hormone levels cannot be cured. These hormones include birth control pills and medications, such as finasteride or spironolactone, that block the effects of male hormones. Women who are pregnant or who could become pregnant should not take a medication that blocks male hormones because it can cause feminine characteristics to develop in a male fetus.

Gonadotropin-releasing hormone agonists (such as leuprolide) can be used if the ovaries are producing extremely high levels of male hormones, but use of these medications requires close supervision by a gynecologist or an endocrinologist. Corticosteroids can be used to reduce levels of male hormones produced by adrenal gland tumors.

Mbinu zingine

Bleaching is an alternative to hair removal. It is inexpensive and works well when women have only a small amount of excess hair. Bleaches lighten the color of the hair, making it less noticeable. Several types of hair-bleaching products are available. Most products contain hydrogen peroxide.

Eflornithine cream, applied twice a day, slows the rate of hair growth and, with long-term use, may increase the amount of time between hair removal treatments.

Mambo Muhimu

  • Excess body hair may run in families, and what is considered excessive may vary with ethnic background and culture.

  • Hirsutism, which occurs only in women, causes excess body hair to grow in a male pattern and differs from hypertrichosis, which occurs in men and women and causes excess hair to grow anywhere on the body.

  • Polycystic ovary syndrome (PCOS) is the most common cause of hirsutism.

  • If women also develop signs of virilization (such as a deepened voice, increased muscle mass, scalp hair loss, or irregular or absent menstrual periods), they may have a hormone disorder that requires prompt evaluation by a doctor.

  • If excess body hair appears suddenly and grows rapidly, the cause may be cancer.

  • Treatment may include hair removal and/or hormonal therapy.