- Muhtasari wa Tatizo la Upungufu wa Kinga Mwilini
- Ataxia-Telangiectasia
- Ugonjwa wa Chédiak-Higashi
- Ugonjwa Sugu wa Granulomatasi (CGD)
- Kandidiasi ya Mucocutaneous ya Muda Mrefu
- Common Variable Immunodeficiency (CVID)
- Ugonjwa wa DiGeorge
- Ugonjwa wa Hyper-IgE
- Ugonjwa wa Hyper-IgM
- Upungufu wa Leukocyte Adhesion
- Upungufu wa kingamwili baguzi za immunoglobulin A (IgA)
- Upungufu wa Kingamaradhi ya Kuchagua Yenye Globulini za Kingamaradhi za Kawaida
- Severe Combined Immunodeficiency (SCID)
- Matatizo ya Wengu na Upungufu wa Kingamaradhi
- Transient Hypogammaglobulinemia ya Utotoni mchanga
- Ugonjwa wa Wiskott-Aldrich
- Agammaglobulinemia inayohusishwa na X
- Ugonjwa wa Lymphoproliferative inayohusishwa na X
- Upungufu wa ZAP-70
ZAP-70 (zeta-associated protein 70) deficiency is a genetic disorder of the immune system that results in an abnormality in T cells that prevents T cells from becoming activated to fight specific infections.
(See also Overview of Immunodeficiency Disorders.)
T cells are white blood cells that identify and attack foreign cells and substances. Deficiency or malfunction of T cells increases the risk of serious infection. ZAP-70 deficiency is a primary immunodeficiency disorder. Its inheritance is autosomal recessive.
ZAP-70 deficiency causes recurrent infections similar to those in severe combined immunodeficiency (SCID) in infants and young children. However, the deficiency may not be diagnosed until children are several years old.
Blood tests are done to measure the number of B cells and T cells and immunoglobulin levels and to evaluate how well B cells and T cells are functioning.
The disorder is fatal unless the child receives a stem cell transplant.
Taarifa Zaidi
The following English-language resource may be useful. Please note that The Manual is not responsible for the content of this resource.
Immune Deficiency Foundation: General information on primary immunodeficiencies, including information on diagnosis and treatment
