Токсичні причини полінейропатій
Type of Neuropathy | Causes |
|---|---|
Axonal motor | With prolonged exposure, lead, mercury |
Axonal sensorimotor | Acrylamide, alcohol (ethanol), allyl chloride, arsenic, cadmium, carbon disulfide, chlorphenoxy compounds, ciguatoxin, colchicine, cyanide, dapsone, disulfiram, DMAPN, ethylene oxide, lithium, methyl bromide, nitrofurantoin, organophosphates, PCBs, PNU, podophyllin, saxitoxin, Spanish toxic oil, taxol, tetrodotoxin, thallium, trichloroethylene, TOCP, vinca alkaloids |
Axonal sensory | Almitrine, bortezomib, chloramphenicol, dioxin, doxorubicin, ethambutol, ethionamide, etoposide, gemcitabine, glutethimide, hydralazine, ifosfamide, interferon alfa, isoniazid, lead, metronidazole, misonidazole, nitrous oxide, nucleosides (didanosine [ddI], stavudine [d4T], zalcitabine [ddC]), phenytoin, platinum analogs, propafenone, pyridoxine, statins, thalidomide |
Demyelinating | Buckthorn, immune checkpoint inhibitors, chloroquine, diphtheria, hexachlorophene, muzolimine, perhexiline, procainamide, tacrolimus tellurium, zimeldine |
Mixed | Amiodarone, ethylene glycol, gold, hexacarbons, n-hexane, sodium cyanate, suramin |
DMAPN = dimethylaminopropionitrile; PCBs = polychlorinated biphenyls; PNU = N-3 pyridylmethyl-N´-p-nitrophenyl urea; TOCP = triorthocresyl phosphate. | |