Гомеопатія

Unlike botanical and nutritional supplements, homeopathic remedies are regulated by the FDA. Only homeopathic remedies that are approved by the FDA can be manufactured. Because so little active ingredient is left after dilution, active ingredients are tested before dilution.

The FDA exempts homeopathic remedies from several requirements that exist for other medications:

• The identity and strength of each active ingredient do not have to be confirmed by a laboratory before the remedy is distributed.

• Manufacturers of homeopathic products are not required to provide evidence of efficacy.

• Homeopathic remedies have been temporarily exempted from limits on the amount of alcohol (the usual diluent) that they can contain.

However, the label is required to list the following:

• Manufacturer

• The term “homeopathic”

• At least one indication

• Instructions for safe use

• Unless specifically exempted, the active ingredient and degree of dilution

The two primary principles of homeopathy are "like cures like" and diluting makes preparations stronger. A preparation diluted so much that it has no active ingredient to have physiologic effects (other than those of a placebo) is biologically and chemically implausible. However, some proclaimed homeopathic preparations do contain active ingredients in concentration sufficient to have physiologic effects (eg, Zicam, which contains a measurable amount of zinc).

Efficacy of homeopathic remedies for various disorders has been extensively studied. A 2010 analysis of systematic reviews found that homeopathy is no more efficacious than placebo for any indication, as did the United Kingdom's House of Commons Science and Technology Committee after an exhaustive review of systematic reviews and meta-analyses of homeopathy (2010) (1,2). The Australian government's exhaustive review of the clinical evidence for homeopathy (2013) found that for 61 indications, there was evidence of lack of efficacy for homeopathy, and for another 7 indications, there was no good-quality evidence (3). Subsequent reviews have reached similar conclusions regarding lack of demonstrated efficacy and low-quality data (4).

Homeopathy continues to be explored given its gentle effect and low likelihood of toxicity. In some clinical conditions lacking clearly beneficial conventional medicine strategies, including fibromyalgia, homeopathy might be considered given data from small studies of potential symptom relief and lack of harm (5, 6).

Homeopathy is commonly used in Europe and India, largely because of a long history of use; as a result, the practice has become part of the culture.

Homeopathy has been used to treat various disorders, such as allergies, rhinitis and respiratory symptoms, digestive problems, musculoskeletal pain, and vertigo.

Homeopathy is well-tolerated and has few risks; rarely, an allergic or toxic reaction occurs.

Additional studies have tried to compare adverse effects of homeopathy and conventional medicine, but additional high quality research is needed to standardize reporting and risk assessment (7). Conventional clinicians should not assume that a homeopathic remedy taken by a patient is biologically inactive and thus could not have adverse effects. Also, some homeopathic remedies contain other active ingredients that can have physiologic effects. Whether patients are taking homeopathic remedies may be unclear because patients often use the term homeopathic erroneously in reference to a dietary supplement they are taking. Also, the FDA allows many medicinal botanicals to be registered and labeled as homeopathic if they undergo a particular pharmaceutical process.

1. 1. Ernst E: Homeopathy: what does the "best" evidence tell us? Med J Aust192(8):458–60, 2010. doi:10.5694/j.1326-5377.2010.tb03585.x

2. 2. United Kingdom's House of Commons Science and Technology Committee: Homeopathy, 2010. Accessed October 2023.

3. 3. National Health and Medical Research Council: Effectiveness of homeopathy for clinical conditions: evaluation of the evidence. Accessed October 2023.

4. 4. Mathie RT, Fok YYY, Viksveen P, et al: Systematic review and meta-analysis of randomised, other-than-placebo controlled, trials of non-individualised homeopathic treatment. Homeopathy 108(2):88-101, 2019. doi: 10.1055/s-0038-1677481

5. 5. Boehm K, Raak C, Cramer H, et al: Homeopathy in the treatment of fibromyalgia—a comprehensive literature-review and meta-analysis. Complement Ther Med 22(4):731-42, 2014. doi: 10.1016/j.ctim.2014.06.005

6. 6. Bell IR, Lewis DA 2nd, Brooks AJ, et al: Improved clinical status in fibromyalgia patients treated with individualized homeopathic remedies versus placebo.Rheumatology (Oxford) 43(5):577–582, 2004. doi: 10.1093/rheumatology/keh111

7. 7. Stub T, Kristoffersen AE, Overvåg G, et al: Adverse effects in homeopathy. A systematic review and meta-analysis of observational studies. Explore (NY) 18(1):114-128, 2022. doi:10.1016/j.explore.2020.11.008