[{"Title":"Симптоми та ознаки","UniqueID":"v904342_uk","Index":1.0,"Summary":"

Almost all patients have recurrent, painful oral ulcers resembling those of aphthous stomatitis; in most, these ulcers are the first manifestations. The ulcers are round or oval, 2 to 10 mm in diameter, and shallow or deep with a central yellowish necrotic center; they can occur anywhere in the oral cavity, often in clusters. Ulcers last 1 to 2 weeks. Similar ulcers occur on the penis and scrotum, on the vulva where they are painful, or in the vagina where they may cause little or no pain.

","HeadType":"F_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[{"Title":"Шкірно-слизовий","UniqueID":"v904344_uk","Index":1.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]},{"Title":"Очний","UniqueID":"v904356_uk","Index":2.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]},{"Title":"М’язовоскелетний","UniqueID":"v904372_uk","Index":3.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]},{"Title":"Судинний","UniqueID":"v904375_uk","Index":4.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]},{"Title":"Неврологічний і психіатричний","UniqueID":"v904379_uk","Index":5.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]},{"Title":"Шлунково-кишковий (ШК)","UniqueID":"v904383_uk","Index":6.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]},{"Title":"Конституційний","UniqueID":"v8495926_uk","Index":7.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]}]},{"Title":"Діагностика","UniqueID":"v904386_uk","Index":2.0,"Summary":"

Clinical criteria

","HeadType":"F_Head","SchemeItemProp":"","Children":[{"Title":"Диференційний діагноз","UniqueID":"v26287465_uk","Index":1.0,"Summary":"

Clinical criteria

","HeadType":"G_Head","SchemeItemProp":"","Children":[]}]},{"Title":"Прогноз","UniqueID":"v904406_uk","Index":3.0,"Summary":"

Behçet disease typically has a waxing and waning course characterized by exacerbations and remissions. Prognosis tends to be worse in young men. Risk also appears to be higher if patients have an HLA-B51 allele. Mucocutaneous and ocular lesions and arthralgias are often worse early in the disease. Central nervous system and large-vessel manifestations, if they develop, typically occur later. Occasionally, the disease results in death, usually due to neurologic, vascular (eg, aneurysms), or gastrointestinal manifestations. Risk of death is highest for young men and patients with arterial disease or a high number of flare-ups. Many patients eventually go into remission.

","HeadType":"F_Head","SchemeItemProp":"","Children":[]},{"Title":"Лікування","UniqueID":"v904409_uk","Index":4.0,"Summary":"

Colchicine, dapsone, azathioprine, apremilast, thalidomide, anti-tumor necrosis factor (TNF) drugs, and/or interferon for mucosal disease

","HeadType":"F_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[{"Title":"Захворювання слизових оболонок","UniqueID":"v26287491_uk","Index":1.0,"Summary":"

Colchicine, dapsone, azathioprine, apremilast, thalidomide, anti-tumor necrosis factor (TNF) drugs, and/or interferon for mucosal disease

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[]},{"Title":"Очне захворювання","UniqueID":"v26287502_uk","Index":2.0,"Summary":"

Colchicine, dapsone, azathioprine, apremilast, thalidomide, anti-tumor necrosis factor (TNF) drugs, and/or interferon for mucosal disease

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[]},{"Title":"Рефрактерне або небезпечне для життя захворювання","UniqueID":"v26287509_uk","Index":3.0,"Summary":"

Colchicine, dapsone, azathioprine, apremilast, thalidomide, anti-tumor necrosis factor (TNF) drugs, and/or interferon for mucosal disease

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[]}]},{"Title":"Ключові моменти","UniqueID":"v8495930_uk","Index":5.0,"Summary":"

Behçet disease is a relapsing inflammatory disorder characterized by prominent mucosal inflammation often with vasculitis of large and small vessels.

","HeadType":"F_Head","SchemeItemProp":"","Children":[]}]