Деякі віруси, які викликають геморагічну лихоманку
Principal Syndromes | Distribution | Specific Therapy | Specific Prevention* |
|---|---|---|---|
Flaviviruses (some) | |||
Former Soviet Union (Siberia) | None | None | |
India, China (Nanjianyin virus) | None | None | |
Africa, Central and South America | None | Yellow fever vaccine for travelers to endemic areas and for populations experiencing an outbreak | |
Tropics and subtropics, worldwide | None | Dengue vaccine for certain people ages 9 to 45 with previous dengue infection | |
Orthohantaviruses (some) | |||
Hemorrhagic fever with renal syndrome due to Hantaan, Puumala, Dobrava (Belgrade), or Seoul virus | Global | Ribavirin | None |
Filoviruses | |||
Lake Victoria Marburg virus disease | Africa | None | None |
Sudan Ebola virus disease | Africa, Sumatra | None | No vaccines approved to date; existing Zaire Ebola vaccines are not effective against the Sudan strain |
Bundibugyo Ebola virus disease | Uganda | None | None |
Zaire Ebola virus disease | Africa | Monoclonal antibody cocktails (FDA approved; compassionate use/expanded access) | rVSV-ZEBOV vaccine approved in US, used in the DRC (Democratic Republic of Congo) outbreaks Ad26.ZEBOV/MVA-BN-Filo vaccine in use in the DRC |
Reston ebolavirus disease | Philippines | None | None |
Mammarenaviruses (some) | |||
Bolivian hemorrhagic fever (due to Machupo virus) Argentinian hemorrhagic fever (due to Junin virus) Venezuelan hemorrhagic fever (due to Guanarito virus) Brazilian hemorrhagic fever (due to Sabia virus) | South America, Africa (only Lassa fever) | Ribavirin Convalescent plasma for all except Lassa fever | Vaccine for Argentinian hemorrhagic fever |
Lujo virus disease | Zambia | None | None |
Orthonairovirus | |||
Crimean-Congo hemorrhagic fever | Tick-borne; former Soviet Union, western Pakistan, Africa, Asia, Middle East, Eastern Europe | Ribavirin | Vaccine (efficacy unknown) |
Phleboviruses (some) | |||
Severe fever with thrombocytopenia syndrome | Tick-borne; China, Korea, Japan | None | None |
* Nonspecific precautions (eg, avoidance of the means of transmission, routine hygiene measures) are also recommended. | |||