Потенційно гепатотоксичні препарати
Finding | Drug |
|---|---|
Hepatocellular: Elevated ALT | Acarbose Acetaminophen Allopurinol Amiodarone ART drugs Bupropion Fluoxetine Germander Green tea extract Baclofen Isoniazid Kava Ketoconazole Lisinopril Losartan Methotrexate NSAIDs Omeprazole PD-1/PD-L1 inhibitors Paroxetine Pyrazinamide Rifampin Risperidone Sertraline Statins Tetracyclines Trazodone Trovafloxacin Valproate |
Cholestatic: Elevated alkaline phosphatase and total bilirubin | Amoxicillin/clavulanate Anabolic steroids Chlorpromazine Clopidogrel Oral contraceptives Erythromycins Estrogens Irbesartan Mirtazapine Phenothiazines Terbinafine Tricyclic antidepressants |
Mixed: Elevated alkaline phosphatase and ALT | Amitriptyline Azathioprine Captopril Carbamazepine Clindamycin Cyproheptadine Enalapril Nitrofurantoin Phenobarbital Phenytoin Sulfonamides Trazodone Trimethoprim/sulfamethoxazole Verapamil |
ALT = alanine aminotransferase; ART = antiretroviral therapy; AST= aspartate aminotransferase; NSAID = nonsteroidal anti-inflammatory drug. | |