Нестероїдні протизапальні препарати (НПЗП)
NSAID | Usual Dosage (Oral) | Maximum Recommended Daily Dose |
|---|---|---|
Nonselective NSAIDs | ||
Diclofenac | 75 mg 2 times a day or 50 mg 3 times a day 100 mg once/day sustained-release | 150 mg |
Etodolac | 300–500 mg 2 times a day | 1200 mg |
Fenoprofen | 300–600 mg 4 times a day | 3200 mg |
Flurbiprofen | 100 mg 2 or 3 times a day | 300 mg |
Ibuprofen | 400–800 mg 4 times a day | 3200 mg |
Indomethacin | 25 mg 3 to 4 times a day 75 mg 2 times a day sustained-release | 200 mg |
Ketoprofen | 50–75 mg 4 times a day 200 mg once/day sustained-release | 300 mg |
Meclofenamate | 50 mg 3 or 4 times a day | 400 mg |
Meloxicam* | 7.5 mg once/day | 15 mg |
Nabumetone | 1000–2000 mg/day in 1 dosage or in divided dosages (500–1000 mg 2 times a day) | 2000 mg |
Naproxen | 250–500 mg 2 times a day | 1500 mg |
Oxaprozin | 1200 mg once/day | 1800 mg |
Piroxicam | 20 mg once/day | 20 mg |
Sulindac | 150–200 mg 2 times a day | 400 mg |
Tolmetin | 400 mg 3 times a day | 1800 mg |
Cyclooxygenase-2 (COX-2) selective NSAIDs | ||
Celecoxib | 200 mg once/day or 2 times a day | 400 mg |
* COX-2 specificity is unclear. | ||