Як відрізнити первинний та вторинний альдостеронізм

Clinical Finding

Primary Aldosteronism

Secondary Aldosteronism

Adenoma

Hyperplasia

Renovascular or Accelerated Hypertension

Edematous Disorders†

Blood pressure

↑↑

↑↑↑↑

N or

Edema

Rare

Rare

Rare

Present

Serum sodium

N or

N or

N or

N or

Serum potassium

N or

N or

N or

Plasma renin activity*

↓↓

↓↓

↑↑

Aldosterone

↑↑

* When corrected for age; older patients have lower mean plasma renin activity.

† Secondary to decreased renal blood flow as in heart failure, cirrhosis, nephrotic syndrome.

↑↑↑↑= very greatly increased; ↑↑= greatly increased; = increased; ↓↓= greatly decreased; = decreased; N = normal.