Прямі судинорозширювальні засоби для лікування гіпертензії

Medication

Selected Adverse Effects*

Comments

Hydralazine

Positive antinuclear antibody test, drug-induced lupus (rare at recommended doses)

Augments vasodilating effects of other vasodilating medication

Minoxidil

Sodium and water retention, hypertrichosis; possibly new or worsening pleural and pericardial effusions

Reserved for severe, refractory hypertension

* Both medications may cause headache, tachycardia, and fluid retention and may precipitate angina in patients with coronary artery disease.