[{"Title":"Довідковий матеріал загального характеру","UniqueID":"v88073248_uk","Index":1.0,"Summary":"

1. Alexandraki KI, Sanpawithayakul K, Grossman A. Adrenal Insufficiency. [Updated 2022 Nov 7]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279083/

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Етіологія","UniqueID":"v982295_uk","Index":2.0,"Summary":"

Approximately 70% of cases in the United States are due to idiopathic atrophy of the adrenal cortex, probably caused by autoimmune processes ( 1 Довідковий матеріал щодо етіології Addison disease is an insidious, usually progressive hypofunctioning of the adrenal cortex. It causes various symptoms, including hypotension and hyperpigmentation, and can lead to adrenal crisis... прочитати більше $\"Довідковий$ ). The remainder result from destruction of the adrenal gland by granuloma (eg, tuberculosis Туберкульоз (ТБ) $\"Туберкульоз$ , histoplasmosis Гістоплазмоз $\"Гістоплазмоз\"$ ), tumor, amyloidosis Амілоїдоз $\"Амілоїдоз\"$ , hemorrhage, or inflammatory necrosis. Hypoadrenocorticism can also result from administration of medications that block corticosteroid synthesis (eg, ketoconazole, the anesthetic etomidate).

","HeadType":"F_Head","SchemeItemProp":"itemprop=\"cause\" itemscope itemtype=\"http://schema.org/MedicalCause\"","Children":[{"Title":"Довідковий матеріал щодо етіології","UniqueID":"v88073257_uk","Index":1.0,"Summary":"

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"cause\" itemscope itemtype=\"http://schema.org/MedicalCause\"","Children":[]}]},{"Title":"Патофізіологія","UniqueID":"v982300_uk","Index":3.0,"Summary":"

Both mineralocorticoids and glucocorticoids are deficient.

","HeadType":"F_Head","SchemeItemProp":"","Children":[{"Title":"Мінералокортикоїдний дефіцит","UniqueID":"v982303_uk","Index":1.0,"Summary":"

Both mineralocorticoids and glucocorticoids are deficient.

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Дефіцит глюкокортикоїдів","UniqueID":"v982308_uk","Index":2.0,"Summary":"

Both mineralocorticoids and glucocorticoids are deficient.

","HeadType":"G_Head","SchemeItemProp":"","Children":[]}]},{"Title":"Клінічні симптоми та ознаки","UniqueID":"v982314_uk","Index":4.0,"Summary":"

Weakness, fatigue, and orthostatic hypotension are early symptoms and signs of Addison disease.

","HeadType":"F_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[{"Title":"Криз надниркових залоз","UniqueID":"v982320_uk","Index":1.0,"Summary":"

Weakness, fatigue, and orthostatic hypotension are early symptoms and signs of Addison disease.

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"signOrSymptom\" itemscope itemtype=\"http://schema.org/MedicalSignOrSymptom\"","Children":[]}]},{"Title":"Діагностика","UniqueID":"v982325_uk","Index":5.0,"Summary":"

Electrolyte levels

","HeadType":"F_Head","SchemeItemProp":"","Children":[{"Title":"Диференційний діагноз","UniqueID":"v982429_uk","Index":1.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Дослідження","UniqueID":"v982440_uk","Index":2.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Провокаційна проба","UniqueID":"v26440905_uk","Index":3.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]},{"Title":"Дослідження для визначення етіології","UniqueID":"v26440958_uk","Index":4.0,"Summary":"

Electrolyte levels

","HeadType":"G_Head","SchemeItemProp":"","Children":[]}]},{"Title":"Лікування","UniqueID":"v982457_uk","Index":6.0,"Summary":"

Hydrocortisone or prednisolone

","HeadType":"F_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[{"Title":"Лікування кризу надниркових залоз","UniqueID":"v982473_uk","Index":1.0,"Summary":"

Hydrocortisone or prednisolone

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[]},{"Title":"Лікування ускладнень","UniqueID":"v982481_uk","Index":2.0,"Summary":"

Hydrocortisone or prednisolone

","HeadType":"G_Head","SchemeItemProp":"itemprop=\"possibleTreatment\" itemscope itemtype=\"http://schema.org/MedicalTherapy\"","Children":[]}]},{"Title":"Ключові моменти","UniqueID":"v6576215_uk","Index":7.0,"Summary":"

Addison disease is primary adrenal insufficiency.

","HeadType":"F_Head","SchemeItemProp":"","Children":[]}]