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Medication	Comments
Oral antihistamines
DimenhydrinateDimenhydrinate	Used to treat vomiting of labyrinthine etiology (eg, motion sickness, labyrinthitis) For promethazine (an H1 antihistamine): Used short-term (eg, for postoperative or acute vertigo)For promethazine (an H1 antihistamine): Used short-term (eg, for postoperative or acute vertigo)
MeclizineMeclizine
PromethazinePromethazine
5-HT3 antagonists
DolasetronDolasetron	Used to treat severe or refractory vomiting, or vomiting caused by chemotherapy Possible adverse effects: Constipation, diarrhea, abdominal pain
GranisetronGranisetron
OndansetronOndansetron
PalonosetronPalonosetron
Other medications
AprepitantAprepitant	Used with highly emetogenic chemotherapy regimens Possible adverse effects: Somnolence, fatigue, hiccups
MetoclopramideMetoclopramide	Used to treat mild vomiting
PerphenazinePerphenazine	Used to treat nausea and vomiting
ProchlorperazineProchlorperazine	Used to treat nausea and vomiting
OlanzapineOlanzapine	Used to treat nausea and vomiting Possible adverse effects: Sedation, cognitive and motor impairment
ScopolamineScopolamine	Used to treat motion sickness Possible adverse effects: Diminished sweating, dry skin