Some Indications for TMP/SMX
Indication | Comments |
|---|---|
Bacterial prostatitis | Primary alternative to fluoroquinolones |
Uncomplicated cystitis in women | As effective as fluoroquinolones for empiric short-course (3-day) therapy if the rate of TMP/SMX resistance is < 15% |
Prophylaxis for recurrent urinary tract infections in women and recurrent urinary tract infections in children | Use of 1/2 to 1 double-strength tablet every night or every other night or, for women with previous recurrences after coitus, after coitus |
Treatment of Pneumocystis jirovecii pneumonia and prophylaxis of this infection in patients with AIDS or cancer | Medication of choice |
Intestinal infections due to various bacteria (eg, Shigella species, Vibrio species, Escherichia coli) and the protozoans Cystoisospora and Cyclospora species | Usefulness limited by increasing prevalence of resistance |
Nocardia and Listeria monocytogenes infections | — |
Community-associated methicillin-resistant Staphylococcus aureus infections | Medication of choice for oral treatment of uncomplicated infections caused by community-associated methicillin-resistant S. aureus |
TMP/SMX = | |