Effect of Aging on Metabolism* and Elimination of Some Drugs
Class or Category | Decreased Hepatic Metabolism | Decreased Renal Elimination |
|---|---|---|
Analgesics and anti-inflammatory drugs | ||
Antidiabetic drugs | — | Chlorpropamide |
Antimicrobial agents | — | |
Cardiovascular drugs | N-Acetylprocainamide | |
Diuretics | — | |
Psychoactive drugs | ||
Others‡ | ||
* When aging’s effect on hepatic metabolism of a drug is controversial, effects reported in the majority of studies are listed. | ||
† The effect occurs in men but not in women. | ||
‡ The drugs listed are examples only and not an exhaustive list. | ||
In these topics