Drugs That Can Cause Serotonin Syndrome
Class | Drugs |
|---|---|
Antidepressants: Monoamine oxidase inhibitors | Isocarboxazid Linezolid Phenelzine Selegiline Tranylcypromine |
Antidepressants: Serotonin-norepinephrine reuptake inhibitors | Bupropion Nefazodone Trazodone Venlafaxine |
Antidepressants: Selective serotonin reuptake inhibitors (SSRIs) | Citalopram Escitalopram Fluoxetine Fluvoxamine Paroxetine Sertraline |
Antidepressants: Tricyclic antidepressants | Amitriptyline Amoxapine Desipramine Doxepin Imipramine Maprotiline Nortriptyline Protriptyline Trimipramine |
Central nervous system (CNS) stimulants | Amphetamine Cocaine Diethylpropion Methamphetamine 3,4-Methylenedioxyamphetamine (MDA) 3,4-Methylenedioxymethamphetamine (MDMA, or Ecstasy) Methylphenidate Phentermine Sibutramine |
Hallucinogens | Lysergic acid diethylamide (LSD) 5-Methoxy-diisopropyltryptamine |
Herbs | Nutmeg Panax (Asian or American) ginseng St John’s wort Syrian rue |
5-Hydroxytryptamine (5-HT1) agonists (triptans) | Almotriptan Eletriptan Frovatriptan Naratriptan Rizatriptan Sumatriptan Zolmitriptan |
Opioids | Buprenorphine Fentanyl Hydrocodone Meperidine Oxycodone Pentazocine Pethidine Tramadol |
Others | Buspirone Chlorpheniramine Dextromethorphan Granisetron 5-Hydroxytryptophan Levodopa Lithium Metoclopramide Olanzapine Ondansetron Risperidone Ritonavir Tryptophan Valproate |