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Causes of Proteinuria

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Mechanism	Examples
Glomerular	Primary glomerular disorders (eg, membranous nephropathy, minimal change disease, focal segmental glomerulosclerosis) Secondary glomerular disorders (eg, diabetic nephropathy, preeclampsia, postinfectious glomerulonephritis, lupus nephritis, amyloidosis)
Tubular	Fanconi syndrome Acute tubular necrosis Tubulointerstitial nephritis Polycystic kidney disease
Overflow	Acute monocytic leukemia with lysozymuria Monoclonal gammopathy Multiple myeloma Myelodysplastic syndromes
Functional or transient proteinuria	Fever Heart failure Intense exercise or activity
Unknown	Orthostatic or postural