Focal Segmental Glomerulosclerosis (IgM in Mesangium)
Immunofluorescence staining with anti-IgM demonstrates IgM in mesangium or in areas of hyalinosis (smooth, globular staining on right). IgM is thought to become trapped in areas of expanded mesangium and sclerosis (×200).
Image provided by Agnes Fogo, MD, and the American Journal of Kidney Diseases' Atlas of Renal Pathology (see www.ajkd.org).
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