Lincosamides, Oxazolidinones, and Streptogramins

ByBrian J. Werth, PharmD, University of Washington School of Pharmacy
Reviewed/Revised May 2024
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    Lincosamides (), oxazolidinones (), and streptogramins (dalfopristin [streptogramin A] and quinupristin [streptogramin B]) are structurally different but are grouped together because they have a similar mode of antibacterial action and similar antibacterial spectra. Macrolides

    Certain methyl-transferase enzymes can mediate resistance to multiple members of the above classes. The (erm (cfr) gene mediates resistance to chloramphenicol, dalfopristin, clindamycin

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