Cathinones are -like stimulants derived from the plant Catha edulis (khat). The khat plant is a shrub grown in East Africa and on the Arabian peninsula. For centuries, people there have chewed the leaves for their mild stimulant effect. In those regions, chewing khat is often a social activity, similar to coffee drinking in other societies.
Recently, khat use has spread to other countries, and much stronger, man-made (synthetic) cathinones (marketed as "bath salts" to circumvent laws regarding controlled substances) have become drugs of abuse. Bath salts can be inhaled, smoked, and sometimes injected. These products, which are frequently labeled "not for human consumption," are not used for bathing.
(See also Drug Use and Abuse.)
Symptoms of Bath Salts Toxicity
The effects of bath salts are similar to those of amphetamines and include headache, a rapid heart rate (tachycardia), palpitations, hallucinations, agitation, and an increased endurance and tolerance for pain. Some people become violent.
Complications
Bath salts can cause a dangerously high body temperature (hyperthermia). They also may cause serious organ damage, although doctors are not sure why. Organ damage can include
Breakdown of muscle (rhabdomyolysis)
Diagnosis of Bath Salt Toxicity
A doctor's evaluation
Blood and urine tests
Because bath salts are not detected with routine urine or blood testing, doctors usually base the diagnosis on symptoms in people known to have used the drug. Doctors typically order the following specific tests for anyone showing signs of severe acute bath salt intoxication to check for other problems caused by using bath salts:
Blood tests (to check blood count, levels of electrolytes, and kidney function)
Urine testing for myoglobinuria (to test for muscle destruction)
Electrocardiography (ECG)
Treatment of Bath Salt Toxicity
Observation and monitoring until the person is sober
IV sedatives
IV fluids
Typical treatments, which include IV sedatives and fluids and supportive care, are usually adequate. People with dangerously high body temperature (hyperthermia), persistently high heart rate or agitation, and blood tests that suggest possible kidney problems should be hospitalized and monitored for muscle breakdown and heart and kidney damage.
More Information
The following English-language resources may be useful. Please note that THE MANUAL is not responsible for the content of these resources.
National Institute on Drug Abuse (NIDA): Cathinone-specific information from the federal agency that supports scientific research into drug use and its consequences and supplies information about commonly used drugs, research priorities and progress, clinical resources, and grant and funding opportunities.
Substance Abuse and Mental Health Services Administration (SAMHSA): US Department of Health agency that leads public health efforts to improve behavioral health and provides resources, including treatment locators, toll-free helplines, practitioner training tools, statistics, and publications on a variety of substance-related topics.
