- Overview of Interstitial Lung Diseases
- Overview of Idiopathic Interstitial Pneumonias
- Acute Interstitial Pneumonia
- Cryptogenic Organizing Pneumonia
- Idiopathic Pleuroparenchymal Fibroelastosis
- Idiopathic Pulmonary Fibrosis
- Lymphoid Interstitial Pneumonia
- Nonspecific Interstitial Pneumonia
- Respiratory Bronchiolitis–Associated Interstitial Lung Disease and Desquamative Interstitial Pneumonia
- Drug-Induced Pulmonary Disease
- Eosinophilic Pneumonia
- Hypersensitivity Pneumonitis
- Lymphangioleiomyomatosis
- Pulmonary Alveolar Proteinosis
- Pulmonary Langerhans Cell Histiocytosis
Drug-induced pulmonary disease is not a single disorder. Many drugs can cause lung problems in people who have no other lung disorders. The type of problem depends on the drug involved, but many of the drugs are thought to cause an allergic-type reaction. The disease is often more severe in older adults. When not caused by an allergic-type reaction, the extent and severity of the disease are sometimes related to how large the drug dose was and for how long the drug was taken.
Depending on the drug, people develop cough, wheezing, shortness of breath, or other lung symptoms. Symptoms may develop:
Slowly over weeks to months
Suddenly and become severe
Diagnosis and treatment are the same, stopping the drug and observing whether the person's symptoms lessen. Doctors will typically prescribe the least toxic drug possible, depending on the condition being treated.
Doctors may do pulmonary function testing or do imaging of the lungs before people begin taking drugs (especially anticancer drugs and radiation therapy) that are known to cause lung problems, but the benefits of screening for prediction or early detection of drug-induced pulmonary disease are unknown.
(See also Overview of Interstitial Lung Diseases.)
