Vitamin E Excess

(Vitamin E Toxicity)

ByLarry E. Johnson, MD, PhD, University of Arkansas for Medical Sciences
Reviewed/Revised Aug 2024
VIEW PROFESSIONAL VERSION

Vitamin E toxicity is rare, but occasionally high doses cause a risk of bleeding, as well as muscle weakness, fatigue, nausea, and diarrhea.

  • Diagnosis is based on a person's symptoms.

Vitamin E (tocopherol) is an antioxidant: It protects cells against damage by free radicals, which are by-products of normal cell activity and which participate in chemical reactions within cells. Some of these reactions can be harmful. (See also Overview of Vitamins.)

Vitamin E supplements do not protect against cancer or heart and blood vessel disorders. There is no convincing evidence that vitamin Evitamin E supplements increase or decrease the risk of stroke.

Vitamin E, like vitamins A, D, and K, is a fat-soluble vitamin, which dissolves in fat and is best absorbed when eaten with some fat. Good sources of vitamin E include vegetable oils, nuts, seeds, green leafy vegetables, and wheat germ.

Symptoms of Vitamin E Excess

Many adults take relatively large amounts of vitamin E

Diagnosis of Vitamin E Excess

The diagnosis of vitamin E toxicity is based on the person’s history of using vitamin E supplements and symptoms.

Treatment of Vitamin E Excess

Treatment of vitamin E

If necessary, vitamin K, which helps blood clot, is given to stop bleeding.

quizzes_lightbulb_red
Test your KnowledgeTake a Quiz!
Download the free MSD Manual App iOS ANDROID
Download the free MSD Manual App iOS ANDROID
Download the free MSD Manual App iOS ANDROID