Dosierung oraler Tuberkulose-Medikamente erster Wahl*

Isoniazid

Erwachsene (maximal)

5 mg/kg (300 mg)

15 mg/kg (900 mg)

15 mg/kg (900 mg)

15 mg/kg (900 mg)

Kinder (maximal)

10–20 mg/kg (300 mg)

N/A

20–40 mg/kg (900 mg)

N/A

Rifampicin

Erwachsene (maximal)

10 mg/kg (600 mg)

N/A

10 mg/kg (600 mg)

10 mg/kg (600 mg)

Kinder (maximal)

10–20 mg/kg (600 mg)

N/A

10–20 mg/kg (600 mg)

N/A

Rifabutin

Erwachsene (maximal)

5 mg/kg (300 mg)

N/A

5 mg/kg (300 mg)

5 mg/kg (300 mg)

Kinder

10–20 mg/kg (300 mg)

N/A

10–20 mg/kg (300 mg)

10–20 mg/kg (600 mg)

Rifapentin‡

Erwachsene

N/A

10 mg/kg (600 mg)

N/A

N/A

Kinder

N/A

N/A

N/A

N/A

Pyrazinamid

Erwachsene (ganze Tabletten):

40–55 kg

1 g

N/A

2 g

1,5 g

56–75 kg

1,5 g

N/A

3 g

2,5 g

≥ 76 kg§

2 g

N/A

4 g

3 g

Kinder (maximal)

15–30 mg/kg (2 g)

N/A

50 mg/kg (2 g)

N/A

Ethambutol

Erwachsene (ganze Tabletten):

40–55 kg

800 mg

N/A

2000 mg

1200 mg

56–75 kg

1200 mg

N/A

2800 mg

2000 mg

≥ 76 kg§

1600 mg

N/A

4000 mg

2400 mg

Kinder (maximal)

15–20 mg/kg (1 g)

N/A

50 mg/kg (2,5 g)

N/A

Moxifloxacin

≥ 12 Jahre alt

400 mg

N/A

N/A

N/A