Пероральні інгібітори фосфодіестерази типу 5 для еректильної дисфункції
Drug | Dose* | Onset of Action | Comments |
|---|---|---|---|
Avanafil | 50, 100, or 200 mg | 30 minutes | Can be taken 15 minutes before intercourse |
Sildenafil | Initial: 50 mg Maintenance: 25‒100 mg (most men respond best to 100 mg) | 60 minutes | Duration of action: ≈ 4 hours; take on empty stomach |
Tadalafil | 10‒20 mg | 60 minutes | Duration of action: 24‒36 hours |
Tadalafil, low-dose | 2.5‒5 mg | 60 minutes | For daily use, taken at about the same time each day, without regard to timing of sexual activity For daily use in patients who also need treatment of benign prostatic hyperplasia |
Vardenafil | 10‒20 mg | 60 minutes | Duration of action: ≈ 4 hours |
Vardenafil, orally disintegrating form | 10 mg | 30 minutes | Can be taken 30 minutes before intercourse |
* Some PDE5 inhibitors such as sildenafil should be taken on an empty stomach at least 1 hour before sexual intercourse except as noted. Maximum frequency is once a day unless otherwise noted. | |||
PDE5 = phosphodiesterase type 5. | |||