Hepatitis B Serology*

Marker

Acute HBV Infection

Chronic HBV Infection

Prior HBV Infection†

Prior HBV Vaccination

HBsAg

+

+

-

Anti-HBs

+

+

IgM anti-HBc

+

-

IgG anti-HBc

+

±

-

HBeAg

±

±

-

Anti-HBe

±

±

-

HBV-DNA

+

+

-

* Antibody to hepatitis D virus (anti-HDV) levels should be measured if serologic tests confirm HBV and infection is severe.

† Patients have had HBV infection and recovered.

Anti-HBc = antibody to hepatitis B core; anti-HBe = antibody to HBeAg; anti-HBs = antibody to HBsAg; HBeAg = hepatitis B e antigen; HBsAg = hepatitis B surface antigen; HBV = hepatitis B virus.

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