Simplified Pulmonary Embolism Severity Index (sPESI)

 

		Age >80 years old (1 point)
		History of cancer (1 point)
		Chronic cardiopulmonary disease (1 point)
		Pulse ≥110 beats/minute (1 point)
		Systolic blood pressure <100 mmHg (1 point)
		Oxygen saturation <90% at diagnosis of P.E. (1 point)

 

Total Criteria Point Count:
 

 

sPESI Score Interpretation

 

0 points:	Low risk of 30-day mortality
1 to 6 points:	High risk of 30-day mortality

 

Notes

• In the Lankeit study of the Simplified PESI an sPESI score of 1 or more was predictive of high risk of adverse outcomes with a sensitivity of 94% and specificity of 40%
• The high-sensitivity troponin T test was also found to predict adverse events when hsTnT is ≥14 pg/mL with a sensitivity of 87% and specificity of 42%
• When both sPESI and hsTnT high risk indicators were present, the sensitivity rose to 100% but specificity fell to 26%

 

References

1. Dunn AS. ACP Journal Club. The simplified Pulmonary Embolism Severity Index and high-sensitivity troponin T predicted prognosis in PE. Ann Intern Med. 2012; 156:JC4-12. PubMed ID: 22508752
2. Jimenez D, Aujesky D, Moores L, et al., RIETE Investigators. Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med. 2010; 170:1383. PubMed ID: 20696966
3. Lankeit M, Jimenez D, Kostrubiec M, et al. Predictive value of the high-sensitivity troponin T assay and the simplified Pulmonary Embolism Severity Index in hemodynamically stable patients with acute pulmonary embolism: a prospective validation study. Circulation. 2011, 13;124:2716. PubMed ID: 22082681