SIRS Criteria: Systemic Inflammatory Response Syndrome

 

Input
 

Temperature		degC degF
Pulse		beats/min
Respiratory Rate		breaths/min
PaCO2		Pascal atm bar cmH2O cmHg ftH2O gm/sqcm inH2O inHg kPa mbar mmHg psi torr
WBC		#/mcL #/microL /mcL /microL 10E+9/L Mill/mcl Thous/mcL X10E+09/L cells/mcL cells/microL x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L
WBC Band Percent		% fraction ratio

 

Results
 

SIRS Score		# index none number points score

 

SIRS interpretation

 

0 to 1 point:	SIRS not present
2 to 4 points:	SIRS present

 

 

 
Equations used
 

SIRSScore = TempFactor + PulseFactor + WBCFactor + RespFactor

 

 

Calculation Details and Variables

• TempFactor is assigned values by this ordered logic:
  • If Temperature >38 degC TempFactor = 1
  • Else if Temperature ≥36 degC TempFactor = 0
  • Else TempFactor = 1.
• PulseFactor is assigned values by this ordered logic:
  • If Pulse >90 beats/min PulseFactor = 1
  • Else PulseFactor = 0.
• The RespFactor is set to 1 when the RespiratoryRate is >20 breaths/min or the PaCO₂ is <20 mmHg. Otherwise the RespFactor is set to 0.
• The WBCFactor is set to 1 if the WBC is <4,000 #/microL, the WBC >12,000 #/microL, or the WBCBandPercent is >10%. Otherwise the WBCFactor is dset to 0.

 

References

1. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest. 1992 Jun;101(6):1644-55. PubMed ID: 1303622