PELD Score for End-Stage Liver Disease (patients less than 12 years old)

 

Input
 

Sex	Female
	Male
Age		mo yr
Weight		kg lb
Height		cm in m
Albumin		gm/L gm/dL mg% mg/dL mg/mL
Bilirubin		gm/L gm/dL mg% mg/dL mg/mL
INR		% fraction ratio
Listing	Age at listing 1 year or older
	Age at listing less than 1 year
Exception diagnoses	Non contributory
	Urea cycle disorder
	Organic acidemia
	Hepatoblastoma

 

Results
 

Growth Failure
PELD score

 

 

Notes

• The Pediatric End-stage Liver Disease, or PELD Score, is used to estimate relative disease severity and likely survival of patients awaiting liver transplantation.
• The Growth term in the equation is set to 0.667 when the subject's height or weight is less than 2 S.D. below the mean values for that age. Thus, the presence of Growth Failure contributes almost 7 points to the PELD score.
• The Listing Age Factor term will be set to 0.436 if the subject is under 1 year of age, or if the subject is less than 2 years old AND was listed before the age of 1 year.
• Exception Diagnoses: UNOS specifies urea cycle disorders, organic acidemia and hepatoblastoma as exceptions to the PELD score calculation (and MELD score in patients between 12 and 17 years old). For patients with these diseases, the PELD score is set at 30. Other metabolic diseases may be considered for exception scores by direct petition to UNOS.
• The United Network for Organ Sharing (UNOS) keeps track of such patients, and has much more information about the PELD score at http://optn.transplant.hrsa.gov/resources/professionalResources.asp?index=8

 
Equations used
 

AgeMonths = Age * 12

HgtM = rangeN1(n2Height, AgeMonths)

WgtM = rangeN1(n2Weight, AgeMonths)

HgtF = rangeN1(n1Height, AgeMonths)

WgtF = rangeN1(n1Weight, AgeMonths)

PELDscore = (!Exceptiondiagnoses * (10 * ((0.480 * ln(Bilirubin)) + (1.857 * ln(INR)) - (0.687 * ln(Albumin)) + ListingAgeFactor + Growth))) + (Exceptiondiagnoses * 30)