Glomerular filtration rate estimate by abbreviated MDRD study equation

 

Input
 

Serum creatinine		mcmol/L mg% mg/dL
Creatinine assay	IDMS (175)
	Non-IDMS (186)
Age		mo yr
Sex	Female (0.742)
	Male (1)
Race	Black (1.21)
	Nonblack (1)

 

Result
 

Glomerular filtration rate		mL/min/1.73 m2
Decimal Precision   0 1 2 3

 

Notes

• MDRD study: Modification of Diet in Renal Disease study.
• Isotope dilution mass spectrometry (IDMS) indicates a method for determining creatinine concentration that has been standardized using or traceable to IDMS. Contact laboratory if uncertain as to whether or not reported values are IDMS-traceable.
• You can estimate the glomerular filtration rate from the formula if the serum creatinine concentration is stable.
• The accuracy of the abbreviated MDRD study equation as an estimate of the true glomerular filtration rate is discussed elsewhere in UpToDate.

 
Equations used
 

Glomerularfiltrationrate = Creatinineassay * Serumcreatinine-1.154 * Age-0.203 * Sex * Race

 

 

Calculation Details and Variables

• Equation parameters such as Creatinine assay, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (175), represent the values that will be used.

 

References

1. Levey AS, Greene T, Kusek JW, et al. A simplified equation to predict glomerular filtration rate from serum creatinine. J Am Soc Nephrol. 11:A0828, 2000 (abstr).