Martin Equation for Low Density Lipoprotein (LDL-C)

 

Input
 

Total Cholesterol		mg/dL mmol/L
HDL Cholesterol		mg/dL mmol/L
Triglycerides		mg/dL_Trig

 

Results
 

Non-HDL Cholesterol		mg/dL_NonHDL
Novel Factor
LDL Cholesterol		mg/dL_LDL
Decimal Precision   0 1 2 3

 

 

 

Notes

• Novel Factor represents the triglyceride to VLDL-cholesterol ratio. This ratio varies depending on the Triglycerides and Non-HDL Cholesterol levels.
• The Novel Factor improves accuracy of LDL Cholesterol determination throughout a wide range of triglyceride levels.

 
Equations used
 

Non-HDL Cholesterol = Total Cholesterol - HDL Cholesterol

LDL Cholesterol = Non-HDL Cholesterol - (Triglycerides / Novel Factor)

 

 
Novel Factors based on Triglycerides and Non-HDL Cholesterol
 

Triglycerides [mg/dL]	Non-HDL Cholesterol [mg/dL]
	<100	100-129	130-159	160-189	190-219	≥220
7-49	3.5	3.4	3.3	3.3	3.2	3.1
50-56	4.0	3.9	3.7	3.6	3.6	3.4
57-61	4.3	4.1	4.0	3.9	3.8	3.6
62-66	4.5	4.3	4.1	4.0	3.9	3.9
67-71	4.7	4.4	4.3	4.2	4.1	3.9
72-75	4.8	4.6	4.4	4.2	4.2	4.1
76-79	4.9	4.6	4.5	4.3	4.3	4.2
80-83	5.0	4.8	4.6	4.4	4.3	4.2
84-87	5.1	4.8	4.6	4.5	4.4	4.3
88-92	5.2	4.9	4.7	4.6	4.4	4.3
93-96	5.3	5.0	4.8	4.7	4.5	4.4
97-100	5.4	5.1	4.8	4.7	4.5	4.3
101-105	5.5	5.2	5.0	4.7	4.6	4.5
106-110	5.6	5.3	5.0	4.8	4.6	4.5
111-115	5.7	5.4	5.1	4.9	4.7	4.5
116-120	5.8	5.5	5.2	5.0	4.8	4.6
121-126	6.0	5.5	5.3	5.0	4.8	4.6
127-132	6.1	5.7	5.3	5.1	4.9	4.7
133-138	6.2	5.8	5.4	5.2	5.0	4.7
139-146	6.3	5.9	5.6	5.3	5.0	4.8
147-154	6.5	6.0	5.7	5.4	5.1	4.8
155-163	6.7	6.2	5.8	5.4	5.2	4.9
164-173	6.8	6.3	5.9	5.5	5.3	5.0
174-185	7.0	6.5	6.0	5.7	5.4	5.1
186-201	7.3	6.7	6.2	5.8	5.5	5.2
202-220	7.6	6.9	6.4	6.0	5.6	5.3
221-247	8.0	7.2	6.6	6.2	5.9	5.4
248-292	8.5	7.6	7.0	6.5	6.1	5.6
293-399	9.5	8.3	7.5	7.0	6.5	5.9
400-13975	11.9	10.0	8.8	8.1	7.5	6.7

 

References

1. Martin SS, Blaha MJ, Elshazly MB, et al. Comparison of a novel method vs the Friedewald equation for estimating low-density lipoprotein cholesterol levels from the standard lipid profile. JAMA. 2013 Nov 20;310(19):2061-8. PubMed ID: 24240933