Glomerular Filtration Rate Estimate by CKD-EPI Equation

 

Input
 

Sex	Female      Male
Race	White or Other (1)
	Black (1.159)
Age		mo yr
Serum creatinine		mcmol/L mg% mg/dL mmol/L

 

Result
 

GFR		mL/min/1.73m2
Decimal Precision   0 1 2 3

 

Notes

• GFR is estimated by an equation developed by the Chronic Kidney Disease Epidemiology Collaboration.
• GFR = 141 * min(Serum_creatinine/kappa, 1)^alpha * max(Serum_creatinine/kappa, 1) ^-1.209 * 0.993^Age * Sex * Race
• For females, the following values are used: Sex = 1.018; alpha = -0.329; kappa = 0.7
• For males, the following values are used: Sex = 1; alpha = -0.411; kappa = 0.9

 
Equations used
 

GFR = 141 * Math.min(Serumcreatinine/kappa1),alpha * Math.max(Serumcreatinine/kappa1),-1.209 * 0.993Age * Sex * Race

 

Calculation Details and Variables

• Equation parameters such as Race, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (1), represent the values that will be used.

 

References

1. Levey AS, Stevens LA, Schmid CH, et al. for the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration). A New Equation to Estimate Glomerular Filtration Rate. Ann Intern Med. 2009 May 5;150(9):604-612. PubMed ID: 19414839
2. Hsu CY. ACP Journal Club. CKD-EPI eGFR categories were better than MDRD categories for predicting mortality in a range of populations. Ann Intern Med. 2012 Nov 20;157(10):JC5-12. doi: 10.7326/0003-4819-157-10-201211200-02012. PubMed ID: 23165688
3. Matsushita K, Mahmoodi BK, Woodward M, et al., Chronic Kidney Disease Prognosis Consortium. Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate. JAMA. 2012 May 9;307(18):1941-51. doi: 10.1001/jama.2012.3954. PubMed ID: 22570462
4. Parsh J, Seth M, Aronow H, et al. Choice of Estimated Glomerular Filtration Rate Equation Impacts Drug-Dosing Recommendations and Risk Stratification in Patients With Chronic Kidney Disease Undergoing Percutaneous Coronary Interventions. J Am Coll Cardiol. 2015 Jun 30;65(25):2714-23. PubMed ID: 26112195