Potentially Hepatotoxic Drugs
Finding | Drug |
|---|---|
Hepatocellular: Elevated ALT | ART drugs Germander Kava NSAIDs PD-1/PD-L1 inhibitors Statins Tetracyclines Trovafloxacin Valproate |
Cholestatic: Elevated alkaline phosphatase and total bilirubin | Anabolic steroids Oral contraceptives Erythromycins Estrogens Phenothiazines Tricyclic antidepressants |
Mixed: Elevated alkaline phosphatase and ALT | Sulfonamides |
ALT = alanine aminotransferase; ART = antiretroviral therapy; AST= aspartate aminotransferase; NSAID = nonsteroidal anti-inflammatory drug. | |
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